How are centres included in randomised controlled trials with parallel economic evaluations in the uk?

Should desperate volunteers be included in randomised controlled trials?

Randomised controlled trials (RCTs) sometimes recruit participants who are desperate to receive the experimental treatment. This paper defends the practice against three arguments that suggest it is unethical first, desperate volunteers are not in equipoise. Second clinicians, entering patients onto trials are disavowing their therapeutic obligation to deliver the best treatment; they are follo...

Introducing “Agreement on what to Measure in Randomised Controlled Trials in Burn Care” Research Project

پروژه پژوهشی "توافق درباره‌ی پیامدهای قابل اندازه‌گیری در کارآزمایی های کنترل‌دار مربوط به مراقبت‌های سوختگی" توسط گروهی از پژوهش‌گران با تجربه، در حوزه سوختگی، زیر نظر دکتر Young از کشور انگلستان در حال انجام می‌باشد. هدف نهایی از انجام این مطالعه، تهیه و تدوین مجموعه‌ای از پیامدهای اساسی (core outcome set (COS)) است که در گزارش کارآزمایی های شاهد‌دار تصادفی مربوط به مراقبت‌های سوختگی باید مور...

How are neonatal and maternal outcomes reported in randomised controlled trials (RCTs) in reproductive medicine?

STUDY QUESTION How do randomised controlled trials (RCTs) in reproductive medicine report maternal and neonatal outcomes, specifically singleton live birth? SUMMARY ANSWER Despite the widespread appeal to use singleton live birth as the outcome measure in subfertility trials, 80% of RCTs fail to do so, and fail to report on neonatal and maternal outcomes. WHAT IS KNOWN ALREADY The aim of re...

Randomised controlled trials in cystic fibrosis: what, when and how?

Economic evaluations in cancer clinical trials

Authors: Stephen Goodall and Rosalie Viney Prepared: July 2011 SUMMARY • The aim of economic evaluation is to inform clinical and health system decision making and policy • Every time a decision is made about a new technology or treatment, a decision is also made about resource allocation • Economic evaluation is a formal and systematic comparison of the costs and benefits associated with two o...